Journal article
Small for gestational age is associated with reduced lung function in middle age: A prospective study from first to fifth decade of life
M Tandra, EH Walters, J Perret, AJ Lowe, CJ Lodge, DP Johns, PS Thomas, G Bowatte, PG Davis, MJ Abramson, SC Dharmage, DS Bui
Respirology | Published : 2023
DOI: 10.1111/resp.14379
Abstract
Background and Objective: The association between birth weight, particularly relative to gestational age, and adult lung function is uncertain. We investigated the associations between birth weight relative to gestational age and measures of lung function in middle age, and mediation of these associations by adult height. Methods: Participants in the Tasmanian Longitudinal Health Study who had both known birth weight and lung function assessment at age 45 years were included (n = 849). Linear regression models were fitted to investigate the association between small for gestational age and birth weight with post-bronchodilator lung function measures (forced expiratory volume in 1 second [FEV..
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Awarded by University of Melbourne
Funding Acknowledgements
We acknowledge the TAHS study participants and previous investigators. We thank Professor Mark Jenkins, PhD, Centre for Epidemiology & Biostatistics, The University of Melbourne, Victoria, a TAHS investigator, but not a co-author of this manuscript, for his assistance with obtaining funds and data collection. We also acknowledge all the respiratory scientists who collected data in the lung function laboratories of Tasmania, Victoria, Queensland and New South Wales; the research interviewers, data entry operators and research officers. Finally, we thank the Archives Office of Tasmania for providing data from the 1968 TAHS questionnaires. Research funding: This study was supported by the National Health and Medical Research Council (NHMRC) of Australia under NHMRC project grant scheme (299901, 1021275) and NHMRC European collaborative grant scheme (1101313) as part of ALEC (Ageing Lungs in European Cohorts funded by the European Union's Horizon 2020 research and innovation programme under grant agreement No. 633212); The University of Melbourne; Clifford Craig Medical Research Trust of Tasmania; The Victorian, Queensland & Tasmanian Asthma Foundations; The Royal Hobart Hospital; Helen MacPherson Smith Trust; and GlaxoSmithKline. The funding agencies had no direct role in the conduct of the study, the collection, management, statistical analysis and interpretation of the data, preparation or approval of the manuscript. Open access publishing facilitated by The University of Melbourne, as part of the Wiley - The University of Melbourne agreement via the Council of Australian University Librarians.